Find Your Funding Opportunity
Selective Precision Targeting (SPoT)
Service
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Source |
Final Application Due Date |
Funding Available
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Match Required
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|---|---|---|---|---|
| Health Care |
Federal
HHS |
02-17-2026 | $1.5 M | No Match Required |
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Service
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Source
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Final Application Due Date
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Funding Available
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Match Required
Status
- Expected Number of Awards 5
- Opportunity Type Discretionary
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CFDA
93.350 -- National Center for Advancing Translational Sciences
Description
The National Center for Advancing Translational Science (NCATS) seeks to advance its mission by establishing a new initiative called Selective Precision Targeting (SPoT) to determine a mechanism for precise and on-target therapeutic drug delivery to specific hard-to-reach locations within the human body usingmicrophysiological systems (MPS). Targeted drug-delivery systems, including engineered nanoparticles, extracellular vesicles or focused ultrasound, are methods for delivering medications to a specific area of the body (organ, tissue, or cell) to increase the concentration of the drug in that area. Hard-to-reach locations in the body include the blood–brain barrier, central nervous system, placenta, retina, or a tumor.
More specifically, the initiative goals are to:
- Optimize specific targeting of nanoparticle therapeutics to the target organ/cell of interest
- Assess biodistribution and off-target effects using a multi-organ microphysiological system
- Provide evidence of functional cargo activity
- Determine optimal route of administration
Grant authorities that allow the National Center for Advancing Translational Science (NCATS) to forecast this opportunity are as follows: 42 U.S. Code § 287a - Cures Acceleration Network.
Eligibility
- IHE
- Local Government
- Non-Profit
- Other
- State Government
- Tribal Government
Key Date(s)
- June 27, 2025: Last Updated Date
- June 27, 2025: Forecasted Date
- December 15, 2025: Estimated Post Date
- February 17, 2026: Estimated Application Due Date
- December 17, 2026: Estimated Award Date
- January 18, 2027: Estimated Project Start Date