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For Program Announcement with Special Receipt, Referral, and/or Review Considerations (PAR) for Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Access (X01 Clinical Trial Not Allowed)
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Service Source Final Application Due Date Funding Available Match Required
Health Care Federal
HHS
07-15-2025 N/A No Match
Required
  • Service
  • Source
  • Final Application Due Date
  • Funding Available
  • Match Required
Status
  • Past
  • Current
  • Forecasted
    • Expected Number of Awards 20
    • Opportunity Type Discretionary
    • CFDA

      93.310 -- Trans-NIH Research Support

    Description

    The Environmental influences on Child Health Outcomes Program (ECHO) Office intends to publish a Program Announcement with Special Receipt, Referral, and/or Review Considerations (PAR) to solicit applications to access ECHO Cohort data or biospecimen resources for studying high-priority areas of maternal and child health.

    The PAR will provide opportunities for individuals across the scientific community to leverage non-ECHO funding to conduct ancillary studies on the ECHO Cohort Consortium’s data platform, including assay of ECHO’s large number of biospecimen resources. The ECHO Cohort’s dataset integrates longitudinal data from more than 130,000 maternal and child participants across the U.S. The data include prenatal and child environmental exposures of many kinds, and five primary pediatric outcome areas: pre-, peri-, and postnatal outcomes; upper and lower airway outcomes; obesity and its consequences; neurodevelopment; and positive health. The ECHO Cohort Biorepository includes over 100,000 biospecimen samples, including blood and urine.

    ECHO Cohort ancillary studies should propose to:

    • Study high-priority areas of maternal and child health;
    • Investigate exposures, including the natural and built environments as well as physical, chemical, social, behavioral, and biological factors;
    • Explore outcomes, including but not limited to ECHO’s five priority areas: pre-, peri-, and postnatal outcomes, upper and lower airway, obesity, neurodevelopment, and positive health or well-being; and
    • Elucidate pathways linking these exposures and outcomes.

    ECHO aims to publish the PAR in the early summer of 2025 with an expected application due date in July 2025. The PAR will use the X01 activity code.

    Eligibility
    • IHE
    • Local Government
    • Non-Profit
    • Other
    • State Government
    • Tribal Government
    Additional Eligibility Information

    Eligible investigators and their institutions must have registered System for Award Management, eRA Commons, and grants.gov accounts. At the time of application to the PAR for X01, candidates must provideA Letter of Support from the Steering Committee of the ECHO Cohort ConsortiumEvidence of funds, or having applied for funds, to support the cores and centers of the ECHO Cohort Consortium

    Key Date(s)
    • May 14, 2025: Last Updated Date
    • May 14, 2025: Forecasted Date
    • June 02, 2025: Estimated Post Date
    • July 15, 2025: Estimated Application Due Date
    • September 15, 2025: Estimated Project Start Date
    • September 15, 2025: Estimated Award Date
    Contact Information
    Melissa Zajdel, Ph.D. Office of the Director, NIH Environmental influences on Child Health Outcomes 301-435-5236 melissa.zajdel@nih.gov

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