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Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)
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Service Source Final Application Due Date Funding Available Match Required
Health Care Federal
HHS
10-13-2025 N/A No Match
Required
  • Service
  • Source
  • Final Application Due Date
  • Funding Available
  • Match Required
Status
  • Past
  • Current
  • Forecasted
    • Opportunity Type Discretionary
    • CFDA

      93.233 -- National Center on Sleep Disorders Research

      93.837 -- Cardiovascular Diseases Research

      93.838 -- Lung Diseases Research

      93.839 -- Blood Diseases and Resources Research

      93.840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders

    Description

    The NHLBI intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications to develop and implement a Clinical Coordinating Center (CCC) for investigator-initiated multi-site clinical trials including efficacy, comparative effectiveness, pragmatic and/or implementation research clinical trials. Trials for which this NOFO applies must be relevant to the research mission of the NHLBI and meet the NIH definition of a clinical trial (see NOT-OD-15-015). This NOFO will utilize a bi-phasic, milestone-driven cooperative agreement mechanism of award and runs in parallel with a companion NOFO (FON-HL-25-018) that encourages applications for a collaborating Data Coordinating Center. The objective of the CCC application is to present the scientific rationale for the clinical trial and a comprehensive scientific and operational plan that describes it. Both a CCC application and a collaborating Data Coordinating Center (DCC) application must be submitted on the same application due date for consideration by NHLBI.

    Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.This NOFO will utilize the UG3/UH3 activity code. Investigators with expertise and insights into this area are encouraged to begin to consider applying for this NOFO.

    Eligibility
    • IHE
    • Local Government
    • Non-Profit
    • Other
    • State Government
    • Tribal Government
    Key Date(s)
    • May 09, 2025: Last Updated Date
    • May 09, 2025: Forecasted Date
    • July 11, 2025: Estimated Post Date
    • October 13, 2025: Estimated Application Due Date
    • May 01, 2026: Estimated Award Date
    • July 01, 2026: Estimated Project Start Date
    Contact Information
    Yves Rosenberg, MD, MPH Division of Cardiovascular Sciences National Heart, Lung, and Blood Institute (NHLBI) 301-435-0550 rosenbey@nhlbi.nih.gov

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