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Development of Medications to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
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Service Source Final Application Due Date Funding Available Match Required
Health Care Federal
HHS
10-16-2025 N/A No Match
Required
  • Service
  • Source
  • Final Application Due Date
  • Funding Available
  • Match Required
Status
  • Past
  • Current
  • Forecasted
    • Opportunity Type Discretionary
    • CFDA

      93.279 -- Drug Use and Addiction Research Programs

    Description

    The National Institute on Drug Abuse (NIDA) intends to publish a Notice of Funding Opportunity (NOFO) to support research on the discovery and development of interventions to prevent and treat substance use disorders (SUDs) and overdose. This includes preclinical and clinical research studies that will have high impact and quickly yield the necessary results to advance candidate interventions closer to regulatory approval or clinical adoption. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the UG3/UH3 activity code. Investigators with expertise and insights in the areas of SUD therapeutics discovery and development are encouraged to begin to consider applying for this new NOFO. Collaborative investigations combining expertise in pharmacology, toxicology, medicinal chemistry, neuromodulation, digital interventions, clinical trials, regulatory science, among others, will be encouraged, and these investigators should also begin considering applying for this application.

    Eligibility
    • IHE
    • Local Government
    • Non-Profit
    • Other
    • State Government
    • Tribal Government
    Key Date(s)
    • May 13, 2025: Last Updated Date
    • May 13, 2025: Forecasted Date
    • August 15, 2025: Estimated Post Date
    • October 16, 2025: Estimated Application Due Date
    • July 01, 2026: Estimated Project Start Date
    • July 01, 2026: Estimated Award Date
    Contact Information
    Drew Townsend, Ph.D. National Institute on Drug Abuse (NIDA) 301-443-4577 drew.townsend@nih.gov

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