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Funding Opportunity for NIH Director’s Pioneer Award Program (DP1 Clinical Trial Optional)
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Service Source Final Application Due Date Funding Available Match Required
Health Care Federal
HHS
09-09-2025 $8.1 M No Match
Required
  • Service
  • Source
  • Final Application Due Date
  • Funding Available
  • Match Required
Status
  • Past
  • Current
  • Forecasted
    • Expected Number of Awards 7
    • Opportunity Type Discretionary
    • CFDA

      93.310 -- Trans-NIH Research Support

    Description

    The Office of Strategic Coordination (Common Fund) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for theNIH Director’s Pioneer Award, part of theHigh-Risk, High-Reward Research program. TheNIH Director’s Pioneer Awardsupports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. The Pioneer Award emphasizes the qualities of the investigator and the innovativeness and potential impact of the proposed research. Preliminary data and detailed experimental plans are not requested or required. The proposed research must reflect substantially different ideas from those being pursued in the investigator’s current research program or elsewhere.

    Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful and responsive projects. Investigators of exceptional creativity with a high-risk, high-impact proposal are encouraged to begin to consider applying for this new NOFO. This NOFO will utilize the DP1 (Clinical Trials Optional) activity code.

    Eligibility
    • IHE
    • Local Government
    • Non-Profit
    • Other
    • State Government
    • Tribal Government
    Additional Eligibility Information

    U.S. Territory or Possession,Regional Organization, Eligible Agencies of the Federal Government. Only single PD/PI applications allowed. PD/PIs must commit at least 51% research effort.

    Key Date(s)
    • May 12, 2025: Last Updated Date
    • May 12, 2025: Forecasted Date
    • June 09, 2025: Estimated Post Date
    • September 09, 2025: Estimated Application Due Date
    • September 01, 2026: Estimated Project Start Date
    • September 01, 2026: Estimated Award Date
    Contact Information
    Patricia Labosky, Ph.D. Office of the Director (OD) 301-594-4863 PioneerAwards@mail.nih.gov

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