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Mechanistic Exploration of Therapeutic Targets and Treatable Traits to Improve CNS Outcomes in People with HIV
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Service Source Final Application Due Date Funding Available Match Required
Health Care Federal
HHS
11-11-2025 $3.0 M No Match
Required
  • Service
  • Source
  • Final Application Due Date
  • Funding Available
  • Match Required
Status
  • Past
  • Current
  • Forecasted
    • Expected Number of Awards 6
    • Opportunity Type Discretionary
    • CFDA

      93.242 -- Mental Health Research Grants

    Description

    The National Institute of Mental Health intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research to identify modifiable targets and mechanisms to alleviate clinically relevant central nervous system (CNS) complications in people with HIV. This NOFO supports research that leverages patient derived data and innovative model platforms to identify and validate novel therapeutic targets underlying CNS complications. Building on advances in systems biology, this initiative seeks to identify modifiable mechanisms contributing to CNS dysfunction through clinical studies or pre-clinical model systems. The ultimate goal is to accelerate the development of effective, mechanism-based interventions that address the multifactorial and heterogeneous nature of CNS complications. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.This NOFO will utilize the R01 activity code. Investigators with expertise in systems biology, pre-clinical models, clinical trial methodologies and translational neurobiology should consider applying to this NOFO.

    Eligibility
    • IHE
    • Local Government
    • Non-Profit
    • Other
    • State Government
    • Tribal Government
    Key Date(s)
    • June 09, 2025: Last Updated Date
    • June 09, 2025: Forecasted Date
    • September 11, 2025: Estimated Post Date
    • November 11, 2025: Estimated Application Due Date
    • July 01, 2026: Estimated Project Start Date
    • July 01, 2026: Estimated Award Date
    Contact Information
    Vasudev R Rao, MBBS, MS. National Institute of Mental Health (NIMH) 301-825-3259 vasudev.rao@nih.gov

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