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NIH Director’s Transformative Research Awards (R01 Clinical Trial Optional)
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Service Source Final Application Due Date Funding Available Match Required
Health Care Federal
HHS
09-03-2025 $8.0 M No Match
Required
  • Service
  • Source
  • Final Application Due Date
  • Funding Available
  • Match Required
Status
  • Past
  • Current
  • Forecasted
    • Expected Number of Awards 7
    • Opportunity Type Discretionary
    • CFDA

      93.310 -- Trans-NIH Research Support

    Description

    The Office of Strategic Coordination (Common Fund) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for theNIH Director’s Transformative Research Award, part of theHigh-Risk, High-Reward Research program. TheNIH Director’s Transformative Research Awardsupports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies.Preliminary data and detailed experimental plans are not requested or required.

    Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful and responsive projects. Investigators of exceptional creativity with a high-risk, high-impact proposal are encouraged to begin to consider applying for this new NOFO. This NOFO will utilize the R01 activity code.

    Eligibility
    • IHE
    • Local Government
    • Non-Profit
    • Other
    • State Government
    • Tribal Government
    Key Date(s)
    • May 12, 2025: Last Updated Date
    • May 12, 2025: Forecasted Date
    • June 20, 2025: Estimated Post Date
    • September 03, 2025: Estimated Application Due Date
    • September 18, 2026: Estimated Award Date
    • September 28, 2026: Estimated Project Start Date
    Contact Information
    Patricia Labosky, Ph.D. Office of the Director (OD) 301-594-4863 Transformative_Awards@mail.nih.gov

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