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Aging Mammalian Tissues In Vitro
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Service Source Final Application Due Date Funding Available Match Required
Health Care Federal
HHS
10-15-2025 N/A No Match
Required
  • Service
  • Source
  • Final Application Due Date
  • Funding Available
  • Match Required
Status
  • Past
  • Current
  • Forecasted
    • Opportunity Type Discretionary
    • CFDA

      93.866 -- Aging Research

    Description

    The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that propose interdisciplinary research that aims to develop complex mammalian 3-dimensional (3D) in vitro microphysiological systems (MPS) to model aging and recapitulate aging processes/phenotypes observed in the whole organism in vivo. It is anticipated that the NOFO will primarily focus on human cell-derived MPS (e.g., tissue chip, organ-on-chip, tissue organoids). However, systems developed using cells of nonhuman mammalian origin may be acceptable for benchmarking, system validation, or when their relevance to understanding human aging biology is justified. Projects will be expected to advance the adoption of MPS in aging biology research and as new human-relevant tools for drug discovery.

    It is anticipated that the NOFO will support exploratory research at the early and conceptual stages of project development. Preliminary data will not be required. It is anticipated that an essential feature of responsive applications will be the adoption of a multidisciplinary approach that includes expertise in aging biology and from disciplines such as stem cell biology, tissue and organ physiology, microfluidics, bioengineering, computational biology, pharmacology, and biostatistics.

    Applications are not being solicited at this time. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

    Eligibility
    • IHE
    • Local Government
    • Non-Profit
    • Other
    • State Government
    • Tribal Government
    Key Date(s)
    • June 16, 2025: Last Updated Date
    • June 16, 2025: Forecasted Date
    • August 15, 2025: Estimated Post Date
    • October 15, 2025: Estimated Application Due Date
    • July 15, 2026: Estimated Project Start Date
    • July 15, 2026: Estimated Award Date
    Contact Information
    Tiziana Cogliati, Ph.D. National Institute on Aging (NIA) 240-397-4596 tiziana.cogliati@mail.nih.gov

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