Find Your Funding Opportunity

HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
Bookmarked grants will display in your Account Setting page

Service Source Final Application Due Date Funding Available Match Required
Health Care Federal
HHS
01-07-2027 N/A No Match
Required
  • Service
  • Source
  • Final Application Due Date
  • Funding Available
  • Match Required
Status
  • Past
  • Current
  • Forecasted
    • Opportunity Type Discretionary
    • CFDA

      93.121 -- Oral Diseases and Disorders Research

      93.213 -- Research and Training in Complementary and Integrative Health

      93.233 -- National Center on Sleep Disorders Research

      93.273 -- Alcohol Research Programs

      93.279 -- Drug Abuse and Addiction Research Programs

      93.313 -- NIH Office of Research on Women's Health

      93.395 -- Cancer Treatment Research

      93.837 -- Cardiovascular Diseases Research

      93.838 -- Lung Diseases Research

      93.839 -- Blood Diseases and Resources Research

      93.840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders

      93.846 -- Arthritis, Musculoskeletal and Skin Diseases Research

      93.847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research

      93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders

      93.865 -- Child Health and Human Development Extramural Research

      93.866 -- Aging Research

      93.867 -- Vision Research

    Description

    Reissue of RFA-NS-20-010: The purpose of this funding opportunity announcement (FOA) is to support preclinical optimization and development of safe, effective, and non-addictive small molecule and biologic therapeutics to treat pain. The goal of the program is to accelerate the optimization and development of promising small molecule and biologic hits/leads towards clinical trials. Applicants must have a promising hit/lead, robust biological rationale for the intended approach, and identified assays for optimization of the agent. The scope of this program includes optimization and early development activities, IND-enabling studies, and assembly of Investigational New Drug (IND) application. This is a milestone-driven phased cooperative agreement program involving participation of NIH program staff in the development of the project plan and monitoring of research progress.

    Eligibility
    • IHE
    • Local Government
    • Non-Profit
    • Other
    • State Government
    • Tribal Government
    Additional Eligibility Information

    Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

    Key Date(s)
    • October 31, 2023: Posted Date
    • November 02, 2023: Last Updated Date
    • January 07, 2027: Current Closing Date for Applications
    • January 07, 2027: Application Due Date
    • February 12, 2027: Application Archive Date
    Contact Information

    NIH Grants Information

    grantsinfo@nih.gov

    DROP US A LINE

    Feedback Feedback

    Your opinion is important to us

    • How would you rate your overall experience on our website?

    • How easy is it to find the information you need?

    • How do you rate the look & feel of our website?

    • How could we improve our website?