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SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Not Allowed)
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Service Source Final Application Due Date Funding Available Match Required
Health Care Federal
HHS
01-05-2026 N/A No Match
Required
  • Service
  • Source
  • Final Application Due Date
  • Funding Available
  • Match Required
Status
  • Past
  • Current
  • Forecasted
    • Opportunity Type Discretionary
    • CFDA

      93.113 -- Environmental Health

      93.121 -- Oral Diseases and Disorders Research

      93.172 -- Human Genome Research

      93.173 -- Research Related to Deafness and Communication Disorders

      93.233 -- National Center on Sleep Disorders Research

      93.242 -- Mental Health Research Grants

      93.273 -- Alcohol Research Programs

      93.286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health

      93.350 -- National Center for Advancing Translational Sciences

      93.394 -- Cancer Detection and Diagnosis Research

      93.395 -- Cancer Treatment Research

      93.837 -- Cardiovascular Diseases Research

      93.838 -- Lung Diseases Research

      93.839 -- Blood Diseases and Resources Research

      93.840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders

      93.846 -- Arthritis, Musculoskeletal and Skin Diseases Research

      93.847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research

      93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders

      93.855 -- Allergy and Infectious Diseases Research

      93.859 -- Biomedical Research and Research Training

      93.865 -- Child Health and Human Development Extramural Research

      93.866 -- Aging Research

      93.867 -- Vision Research

    Description

    The National Institutes of Health (NIH), including the following NIH Institutes and Centers (ICs): OD, NEI, NHLBI, NHGRI, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NINDS, NCATS, NCI, NIA, intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications from small business concerns (SBCs) to the Commercialization Readiness Pilot (CRP) program. The NOFO aims to facilitate the transition of previously or currently funded SBIR and STTR Phase II and Phase IIB projects to the commercialization stage by providing additional support for technical assistance and later stage research and development (R&D) not typically supported through Phase II or Phase IIB grants or contracts. This may include independent replication of key studies, Investigational New Drug (IND)-enabling studies, clinical studies, manufacturing costs, regulatory assistance, or a combination of services. Although a significant amount of the work in a CRP award may be subcontracted to other institutions, the Small Business Concern (SBC) is expected to maintain oversight and management of the R&D throughout the award. Applications are not being solicited at this time. Publication of this solicitation is contingent upon reauthorization and extension of the SBIR program. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.This NOFO will utilize the SB1 activity code. Recipients with Phase II or IIB SBIR/STTR awards that have been active within the last 36 months, including those that will be active at the requested start date, within the missions of the NIH awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO.

    Eligibility
    • IHE
    • Local Government
    • Non-Profit
    • Other
    • State Government
    • Tribal Government
    Additional Eligibility Information

    Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity.

    Key Date(s)
    • June 10, 2025: Forecasted Date
    • June 18, 2025: Last Updated Date
    • October 01, 2025: Estimated Post Date
    • January 05, 2026: Estimated Application Due Date
    • June 01, 2026: Estimated Award Date
    • July 01, 2026: Estimated Project Start Date
    Contact Information
    NIH SEED (Small business Education and Entrepreneurial Development) Office of Extramural Research (OER) 301-827-8595 SEEDinfo@nih.gov

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