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Omics Phenotypes Related to Down Syndrome for the INCLUDE Project (X01 Clinical Trial Not Allowed)
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Service Source Final Application Due Date Funding Available Match Required
Health Care Federal
HHS
03-13-2026 N/A No Match
Required
  • Service
  • Source
  • Final Application Due Date
  • Funding Available
  • Match Required
Status
  • Past
  • Current
  • Forecasted
    • Opportunity Type Discretionary
    • CFDA

      93.121 -- Oral Diseases and Disorders Research

      93.172 -- Human Genome Research

      93.173 -- Research Related to Deafness and Communication Disorders

      93.865 -- Child Health and Human Development Extramural Research

    Description

    This Notice of Funding Opportunity (NOFO) invites applications to usethe NIH INCLUDE Project (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) to access resources to generate a large volume of integrated genomic and multi-omics data to facilitate discovery of the molecular mechanisms of health conditions related to Down syndrome. These data, and associated clinical and phenotypic data, will become part of the INCLUDE Project data resource for sharing with the research community. No funding will be provided directly to applicants under this NOFO. Applicants are encouraged to propose omics essays of existing biospecimens collected from individuals with Down syndrome and controls. The program will accept applications that propose whole genome sequencing, including both short-read and long-read, exome, epigenome, and transcriptome sequencing, as well as proteomic, metabolomic, and single-cell RNA sequencing and ATAC sequencing, when justified. Applicants are encouraged to propose cohorts of underrepresented racial and ethnic groups or to increase racial and ethnic representation of existing collections. The omics data and related phenotypic data will be deposited in a public INCLUDE Project controlled-access database.

    Eligibility
    • IHE
    • Local Government
    • Non-Profit
    • Other
    • State Government
    • Tribal Government
    Additional Eligibility Information

    Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

    Key Date(s)
    • December 05, 2023: Last Updated Date
    • December 05, 2023: Posted Date
    • March 13, 2026: Current Closing Date for Applications
    • March 13, 2026: Application Due Date
    • April 18, 2026: Application Archive Date
    Contact Information

    NIH Grants Information

    grantsinfo@nih.gov

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