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NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
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Service Source Final Application Due Date Funding Available Match Required
Health Care Federal
HHS
01-05-2026 N/A No Match
Required
  • Service
  • Source
  • Final Application Due Date
  • Funding Available
  • Match Required
Status
  • Past
  • Current
  • Forecasted
    • Opportunity Type Discretionary
    • CFDA

      93.068 -- Chronic Diseases: Research, Control, and Prevention

      93.070 -- Environmental Public Health and Emergency Response

      93.073 -- Birth Defects and Developmental Disabilities - Prevention and Surveillance

      93.083 -- Prevention of Disease, Disability, and Death through Immunization and Control of Respiratory and Related Diseases

      93.084 -- Prevention of Disease, Disability, and Death by Infectious Diseases

      93.103 -- Food and Drug Administration Research

      93.113 -- Environmental Health

      93.121 -- Oral Diseases and Disorders Research

      93.136 -- Injury Prevention and Control Research and State and Community Based Programs

      93.142 -- NIEHS Hazardous Waste Worker Health and Safety Training

      93.143 -- NIEHS Superfund Hazardous Substances_Basic Research and Education

      93.172 -- Human Genome Research

      93.173 -- Research Related to Deafness and Communication Disorders

      93.213 -- Research and Training in Complementary and Integrative Health

      93.233 -- National Center on Sleep Disorders Research

      93.242 -- Mental Health Research Grants

      93.262 -- Occupational Safety and Health Program

      93.273 -- Alcohol Research Programs

      93.279 -- Drug Use and Addiction Research Programs

      93.286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health

      93.307 -- Minority Health and Health Disparities Research

      93.316 -- Public Health Preparedness and Response Science, Research, and Practice

      93.326 -- Strengthening Public Health through Surveillance, Epidemiologic Research, Disease Detection and Prevention

      93.350 -- National Center for Advancing Translational Sciences

      93.351 -- Research Infrastructure Programs

      93.361 -- Nursing Research

      93.393 -- Cancer Cause and Prevention Research

      93.394 -- Cancer Detection and Diagnosis Research

      93.395 -- Cancer Treatment Research

      93.837 -- Cardiovascular Diseases Research

      93.838 -- Lung Diseases Research

      93.839 -- Blood Diseases and Resources Research

      93.840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders

      93.846 -- Arthritis, Musculoskeletal and Skin Diseases Research

      93.847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research

      93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders

      93.855 -- Allergy and Infectious Diseases Research

      93.859 -- Biomedical Research and Research Training

      93.865 -- Child Health and Human Development Extramural Research

      93.866 -- Aging Research

      93.867 -- Vision Research

      93.879 -- Medical Library Assistance

    Description

    The National Institutes of Health (NIH), including the following NIH Institutes and Centers (ICs): NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINDS, NINR, NIMHD, NLM, NCCIH, NCATS, ORIP, NCI and ORWH, along with the Centers for Disease Control (CDC), and the Food and Drug Administration (FDA), intends to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR) Phase I, Phase II, Direct to Phase II (NIH Only), Fast-Track (NIH only), and Phase IIB (NIH only) grant applications. Applications are not being solicited at this time. Publication of this solicitation is contingent upon reauthorization and extension of the SBIR program. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.This NOFO will utilize the R43/R44 activity code. United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH, CDC, and FDA awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise will be encouraged, and these investigators should also begin considering applying for this application.

    Eligibility
    • IHE
    • Local Government
    • Non-Profit
    • Other
    • State Government
    • Tribal Government
    Additional Eligibility Information

    Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity.

    Key Date(s)
    • June 18, 2025: Last Updated Date
    • June 18, 2025: Forecasted Date
    • October 01, 2025: Estimated Post Date
    • January 05, 2026: Estimated Application Due Date
    • June 01, 2026: Estimated Award Date
    • July 01, 2026: Estimated Project Start Date
    Contact Information
    NIH SEED (Small business Education and Entrepreneurial Development) Office of Extramural Research (OER) 301-827-8595 SEEDinfo@nih.gov

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