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NIH Blueprint for Neuroscience: Coordination Center for Interoception Research (BPCCIR) (U24, Clinical Trial Not Allowed)
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Service Source Final Application Due Date Funding Available Match Required
Health Care Federal
HHS
11-10-2025 $700,000 No Match
Required
  • Service
  • Source
  • Final Application Due Date
  • Funding Available
  • Match Required
Status
  • Past
  • Current
  • Forecasted
    • Expected Number of Awards 1
    • Opportunity Type Discretionary
    • CFDA

      93.213 -- Research and Training in Complementary and Integrative Health

    Description

    The NIH Blueprint for Neuroscience Research is a collaborative framework involving 14 NIH Institutes, Centers, and Offices aimed at accelerating neuroscience discoveries and alleviating the burden of nervous system disorders. This Notice forecasts a potential Funding Opportunity (NOFO) for establishing the NIH Blueprint for Neuroscience Research Coordination Center for Interoception Research (BPCCIR). Interoception involves the processes by which an organism senses, interprets, integrates, and regulates internal bodily signals. The BPCCIR aims to promote multidisciplinary interoception research and bridge the gap between brain and body studies through a U24 cooperative agreement funding mechanism.

    Aligned with the NIH Director's priorities, this NOFO focuses on improving population health through innovative research and collaboration by breaking traditional biomedical research boundaries that typically focus on one organ system at a time. The key objectives are to:

    Establish and maintain a multidisciplinary team of interoception researchers to guide BPCCIR activities, ensuring academic freedom and fostering innovative approaches.

    Develop digital communication platforms to facilitate networking, collaborations, and information dissemination, promoting research safety and transparency.

    Plan, organize, and host at least one scientific meeting per year, involving NIH-funded interoception researchers, trainees, and other stakeholders to enhance collaboration and knowledge sharing.

    Identify challenges and future opportunities in interoception research, develop common terminology, data standards, and common data elements to ensure reproducibility and rigor.

    Generate metrics of success and plans to ensure the sustainability of the interoception research community, focusing on long-term improvements in population health.

    Interoception research is critical for health promotion, offering insights into stress regulation, hunger, and emotional well-being —factors essential for preventing chronic diseases and mental health disorders. Impaired interoception is linked to conditions like obesity, diabetes, anxiety, depression, and substance use disorders, which significantly impact the nation's healthcare burden. Advancing interoception research may lead to innovative strategies for disease prevention and treatment of complex diseases such as Alzheimer's, Parkinson's, autism, chronic pain, Post traumatic Stress Disorder (PTSD), Irritable Bowel Syndrome (IBS), fibromyalgia, and cardiovascular diseases.

    Eligible applicants for this funding opportunity include higher education institutions, non-profits, for-profit organizations, governments, and other entities capable of conducting multidisciplinary research. The target audience includes researchers and institutions with expertise in neuroscience, physiology, psychology, and biomedical sciences, all committed to advancing interoception research in alignment with NIH's strategic priorities.

    Eligibility
    • IHE
    • Local Government
    • Non-Profit
    • Other
    • State Government
    • Tribal Government
    Key Date(s)
    • May 05, 2025: Last Updated Date
    • May 05, 2025: Forecasted Date
    • August 11, 2025: Estimated Post Date
    • November 10, 2025: Estimated Application Due Date
    • July 01, 2026: Estimated Project Start Date
    • July 01, 2026: Estimated Award Date
    Contact Information
    Wen Chen 301-451-3989 chenw@mail.nih.gov

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