Find Your Funding Opportunity
Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)
Service
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Source |
Final Application Due Date |
Funding Available
|
Match Required
|
|---|---|---|---|---|
| Health Care |
Federal
HHS |
02-17-2028 | N/A | No Match Required |
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Service
-
Source
-
Final Application Due Date
-
Funding Available
-
Match Required
Status
- Opportunity Type Discretionary
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CFDA
93.121 -- Oral Diseases and Disorders Research
93.242 -- Mental Health Research Grants
93.350 -- National Center for Advancing Translational Sciences
93.855 -- Allergy and Infectious Diseases Research
93.867 -- Vision Research
Description
The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for exploratory and early-stage projects that focus on undruggable target classes within intractable human disease. Applicants will identify a human disease relevant undruggable target class and develop a method or agent that is selective for one or more targets within that target class. This NOFO is intended to jumpstart research that demonstrates innovative strategies to modulate targets that cannot be addressed by established therapeutic types, furthering the development of methods and/or agents selective for undruggable target classes.
Eligibility
- IHE
- Local Government
- Non-Profit
- Other
- State Government
- Tribal Government
Additional Eligibility Information
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Key Date(s)
- June 17, 2025: Last Updated Date
- June 17, 2025: Posted Date
- February 17, 2028: Current Closing Date for Applications
- February 17, 2028: Application Due Date
- March 24, 2028: Application Archive Date
Contact Information
NIH Grants Information
grantsinfo@nih.gov